They have very, very sharp claws. They can cut deeply through your skin very easily. Therefore, it’s best to trim them on a regular basis. You can also keep a few rough surfaces inside the enclosure. This will help keep the nails from growing quickly so you won't have to trim them as often.

If you don’t trim the nails regularly, you should get a quality pair of gloves to wear when handling the iguana. Falconry gloves are the best ones to buy. If you don't have the budget for them, you can get buy with a nice pair of welding gloves.

Another common method of attack is biting. They have plenty of sharp teeth to bite you with. If an iguana gets a good grip on you, it can be very hard to get him off. While trying to get him off, you may also cause him to lose some teeth. Gloves also help prevent biting.

The tail whip is also a common attack from aggressive iguanas. Although it won’t cause much damage, it can be very painful. However, it’ll be a different story if you’re whipped in the face or eyes specifically. You can minimize the damage caused by a tail whip by getting closer to the iguana so he can’t extend his tail as far.

It’s also common for aggressive iguanas to jump at you for an aerial attack. A jump attack can leave you open to be bitten or scratched. These lizards can leap quite a few feet, so you’ll need to keep your distance to prevent it from happening.